GenBio AI previews virtual cell simulator AIDO Cell

GenBio AI has previewed AIDO Cell, a general-purpose human cell simulator intended to let researchers run virtual genetic and chemical interventions before wet lab work. The model combines DNA, RNA, proteins, regulatory networks and whole-cell behavior, moving beyond tools focused on isolated tasks such as protein structure prediction, binding or gene expression analysis.

The preview focuses on K-562 and Hep-G2, two well-studied human cell lines supported by extensive multi-omics data. A persistent cellular state allows sequential experiments, so scientists can apply an intervention, observe changes and then run further perturbations on the updated virtual cell. Users can simulate gene knockouts, knockdowns, overexpressions or small-molecule treatments, with readouts spanning chromatin accessibility, expression profiles, protein structures and interactions, localization and morphology.

In benchmarks spanning 31 metrics across five task families, AIDO Cell 1.0 claims state-of-the-art results on 24, while remaining competitive with specialist systems including AlphaFold 3, isoDDE and AlphaGenome. The platform also supports in-context molecular design, where researchers define a desired phenotype, generate candidate molecules and test them on cloned virtual cells. Access is currently limited to GenBio’s team and alpha collaborators, with early access planned for academic, biotech and pharmaceutical researchers and expanded versions expected later in 2026 and beyond.