MIT Researchers Develop Mussel- and Mucus-Inspired Germ-Fighting Glue

Researchers from MIT and Germany have unveiled a new adhesive that merges the remarkable stickiness of mussel-inspired polymers with the antimicrobial properties of mucus. The team, including George Degen, a postdoctoral researcher in MIT´s Department of Mechanical Engineering, leveraged the natural abilities of both components: mussels´ fluid secretions, rich in proteins connected by chemical cross-links, and mucin—the main component of mucus known for its germ-resistant qualities.

To develop the new material, the team combined solutions containing natural mucin proteins with synthetic mussel-inspired polymers. This blend prompted a rapid solidification and strong adhesion to various surfaces, even under wet conditions. According to Degen, the process behaves much like a two-part epoxy: when the two liquid ingredients are mixed, they undergo a chemical reaction that solidifies them into a robust, sticky gel capable of tightly binding to surfaces.

The adhesive´s unique germ-fighting feature stems from the mucin proteins, which help inhibit bacterial growth on the glued surfaces. Researchers suggest the gel could be deployed as an injectable or sprayable solution that forms a protective, sticky coating upon application. Potential applications include coating medical implants to reduce infection rates and incorporating natural materials like keratin for use in sustainable packaging. The approach underscores the value of bioinspired innovation in creating multifunctional materials for healthcare and industrial needs.